Bromodiphenhydramine

Preferred Label : Bromodiphenhydramine;

NCIt synonyms : Bromazine; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-n,n-dimethyl-;

NCIt definition : A brominated derivative of diphenhydramine, an ethanolamine derivative and histamine H1 receptor antagonist with anti-allergic, sedative, antiemetic and anticholinergic properties. Bromazine competitively and selectively blocks central and peripheral histamine H1 receptors, thereby alleviating the symptoms caused by endogenous histamine on bronchial, capillary and gastrointestinal (GI) smooth muscles. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, itching, and spasmodic contractions of GI smooth muscle. In addition, bromazine binds to and blocks peripheral and central muscarinic receptors.;

UNII : T032BI7727;

CAS number : 118-23-0;

Chemical formula : C17H20BrNO;

ChEBI ID : CHEBI:59177;

Details

Origin ID

C61654;

UMLS CUI

C0054120;

Currated CISMeF NLP mapping
- Bromazine [ICD-11 Extension code]
- Bromazine [ICHI extension code]
- Bromazine (substance) [SNOMED CT concept]
- Bromodiphenhydramine [LOINC component]
- Product containing bromazine (medicinal product) [SNOMED CT concept]
- bromodiphenhydramine [Substance BNPC]
- bromodiphenhydramine [MeSH concept]
- bromodiphenhydramine [MeSH Supplementary Concept]
- bromodiphenhydramine [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bromazine [ICD-11 Extension code]
- Bromazine (substance) [SNOMED CT concept]
- Bromodiphenhydramine [LOINC component]
- Product containing bromazine (medicinal product) [SNOMED CT concept]
- bromazine [ATC Code]
- bromodiphenhydramine [Substance BNPC]
- bromodiphenhydramine [MeSH concept]
- bromodiphenhydramine [SNOMED Notion]
- bromodiphenhydramine [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- bromazine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Bromodiphenhydramine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Bromodiphenhydramine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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