Preferred Label : Bromodiphenhydramine;
NCIt synonyms : Bromazine; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-n,n-dimethyl-;
NCIt definition : A brominated derivative of diphenhydramine, an ethanolamine derivative and histamine
H1 receptor antagonist with anti-allergic, sedative, antiemetic and anticholinergic
properties. Bromazine competitively and selectively blocks central and peripheral
histamine H1 receptors, thereby alleviating the symptoms caused by endogenous histamine
on bronchial, capillary and gastrointestinal (GI) smooth muscles. This prevents histamine-induced
bronchoconstriction, vasodilation, increased capillary permeability, itching, and
spasmodic contractions of GI smooth muscle. In addition, bromazine binds to and blocks
peripheral and central muscarinic receptors.;
UNII : T032BI7727;
CAS number : 118-23-0;
Chemical formula : C17H20BrNO;
ChEBI ID : CHEBI:59177;
Origin ID : C61654;
UMLS CUI : C0054120;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
