Betaxolol - CISMeF

Preferred Label : Betaxolol;

NCIt synonyms : 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-propanol;

NCIt definition : A racemic mixture and selective beta-1 adrenergic receptor antagonist with antihypertensive and anti-glaucoma activities and devoid of intrinsic sympathomimetic activity. Betaxolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. When applied topically in the eye, this agent reduces aqueous humor secretion and lowers the intraocular pressure (IOP). In addition, betaxolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.;

UNII : O0ZR1R6RZ2;

InChIKey : NWIUTZDMDHAVTP-UHFFFAOYSA-N;

CAS number : 63659-18-7;

Chemical formula : C18H29NO3;

ChEBI ID : CHEBI:3082;

Details

Origin ID

C61652;

UMLS CUI

C0005320;

Automatic exact mappings (from CISMeF team)
- Levobetaxolol (substance) [SNOMED CT concept]
- pre dose betaxolol [LOINC Challenge]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Betaxolol [ICD-11 Extension code]
- Betaxolol [LOINC Challenge]
- Betaxolol (substance) [SNOMED CT concept]
- Product containing betaxolol (medicinal product) [SNOMED CT concept]
- betaxolol [ATC Code]
- betaxolol [ATC Code]
- betaxolol [MeSH concept]
- betaxolol [MeSH Descriptor]
Validated automatic mappings to BTNT
- betaxolol [ATC Code]
- betaxolol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Betaxolol Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Betaxolol Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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