Arformoterol - CISMeF

Preferred Label : Arformoterol;

NCIt definition : A long-acting beta-2 adrenergic agonist and isomer of formoterol with bronchodilator activity. Arformoterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle and lead to a reduced release of inflammatory mediators from mast cells. This may eventually lead to an improvement of airway function.;

UNII : F91H02EBWT;

InChIKey : BPZSYCZIITTYBL-YJYMSZOUSA-N;

CAS number : 67346-49-0;

Chemical formula : C19H24N2O4;

ChEBI ID : CHEBI:408174;

Details

Origin ID

C61641;

UMLS CUI

C0969589;

Automatic exact mappings (from CISMeF team)
- Formoterol Fumarate [MeSH Descriptor]
- Product containing arformoterol (medicinal product) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Arformoterol (substance) [SNOMED CT concept]
- arformoterol [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Arformoterol (substance) [SNOMED CT concept]
- Product containing arformoterol (medicinal product) [SNOMED CT concept]
- arformoterol [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Arformoterol Tartrate [NCIt concept]
is_free_acid_or_base_form_of
- Arformoterol Tartrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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