NCIt related terms : PABA; para-aminobenzoic acid;
NCIt definition : An organic acid with UV absorption and antifibrotic properties. When exposed to light,
aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess
energy via a photochemical reaction that may cause damage to DNA. Because DNA defects
contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen
formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level
and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin,
which in excess, may lead to fibrotic changes.;
Alternative definition : NCI-GLOSS: A nutrient in the vitamin B complex that the body needs in small amounts
to function and stay healthy. Bacteria that live in the intestines need aminobenzoic
acid to survive. Aminobenzoic acid is found in grains and foods from animals. It is
being studied as a radiosensitizer (a substance that makes tumor cells more sensitive
to radiation therapy) and in the treatment of certain skin disorders.;
UNII : TL2TJE8QTX;
InChIKey : ALYNCZNDIQEVRV-UHFFFAOYSA-N;
CAS number : 150-13-0;
Chemical formula : C7H7NO2;
ChEBI ID : CHEBI:30753;
Codes from synonyms : CDR0000629146; CDR0000629145; CDR0000556409;