Preferred Label : Melan-A VLP Vaccine;
NCIt synonyms : CYT004-MelQbG10;
NCIt definition : A vaccine consisting of the melanocyte differentiation antigen Melan A (also called
MART-1) encapsulated in noninfectious virus-like particles (VLP) with potential immunostimulating
and antineoplastic activities. Upon administration, Melan-A VLP vaccine may activate
the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against
cancer cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan
A is an antigen that is upregulated in most melanomas. VLP stimulates the immune system
and promotes the CTL response.;
Origin ID : C61495;
UMLS CUI : C1831836;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
