Preferred Label : Alacizumab Pegol;
NCIt synonyms : Pegylated Anti-GRF Antibody Fragment;
NCIt definition : A pegylated, cross-linked, humanized divalent-Fab' antibody fragment directed against
vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antiangiogenic
and antitumor activities. Alacizumab pegol binds to and inhibits VEGFR-2, which may
inhibit angiogenesis and tumor cell proliferation. Multivalent Fab' antibody fragments
may exhibit improved retention and internalization properties compared to their parent
IgGs.;
UNII : ZL9780F883;
CAS number : 934216-54-3;
Molecule name : CDP-791;
Origin ID : C61438;
UMLS CUI : C4745258;
Semantic type(s)
- concept_is_in_subset
