Stage IVA Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

Preferred Label : Stage IVA Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7;

NCIt synonyms : Stage IVA Nasopharyngeal Keratinizing Squamous Cell Carcinoma; Stage IVA Keratinizing Epidermoid Carcinoma of Nasopharynx; Stage IVA Keratinizing Squamous Cell Carcinoma of the Nasopharynx; Stage IVA Keratinizing Squamous Cell Carcinoma of Nasopharynx; Stage IVA Nasopharynx Keratinizing Squamous Cell Carcinoma; Stage IVA Nasopharyngeal Keratinizing Epidermoid Carcinoma; Stage IVA Nasopharynx Keratinizing Epidermoid Carcinoma; Stage IVA Keratinizing Epidermoid Carcinoma of the Nasopharynx; Stage IVA Nasopharyngeal Squamous Cell Carcinoma;

NCIt related terms : Stage IVA Nasopharyngeal Throat Keratinizing Squamous Cell Cancer;

NCIt definition : Stage IVA includes: (T4, N0, M0); (T4, N1, M0); (T4, N2, M0). T4: Nasopharyngeal cancer with intracranial extension and/or involvement of cranial nerves, hypopharynx, orbit, or with extension to the infratemporal fossa/masticator space. N0: No regional lymph node metastasis. N1: Nasopharyngeal cancer with unilateral metastasis in cervical lymph node(s), 6 cm or less in greatest dimension, above the supraclavicular fossa, and/or unilateral or bilateral, retropharyngeal lymph nodes, 6 cm or less in greatest dimension. Midline nodes are considered ipsilateral nodes. N2: Nasopharyngeal cancer with bilateral metastasis in cervical lymph node(s), 6 cm or less in greatest dimension, above the supraclavicular fossa. Midline nodes are considered ipsilateral nodes. M0: No distant metastasis. (AJCC 7th ed.);

Neoplastic status : Malignant;

Details

Origin ID

C6137;

UMLS CUI

C1336349;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Headache [NCIt concept]
- Nasal Obstruction [NCIt concept]
- Neck Mass [NCIt concept]
- Rhinorrhea [NCIt concept]
- Tinnitus [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Nasopharynx [NCIt concept]
- Neck [NCIt concept]
- Pharynx [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Keratinizing Malignant Squamous Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Keratin Pearls Formation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Nasopharynx Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Nasopharynx [NCIt concept]
- Neck [NCIt concept]
- Pharynx [NCIt concept]
- Throat [NCIt concept]
disease_is_stage
- AJCC v7 Stage [NCIt concept]
- Stage IV [NCIt concept]
- Stage IVA [NCIt concept]
disease_mapped_to_gene
- HLA-A Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 11q [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 14q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
- Loss of Chromosome 9q [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Protein Overexpression [NCIt concept]
- RASSF1A Gene Inactivation [NCIt concept]

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