Recombinant Gonadorelin

Preferred Label : Recombinant Gonadorelin;

NCIt synonyms : Therapeutic GRH; Gonadorelin; D-His-6-Pro-8-NEt-LHRH; LH-RH; Recombinant Gonadotrophin Releasing Hormone; Therapeutic Gonadorelin;

NCIt definition : A synthetic luteinizing hormone releasing hormone (LHRH) identical to or similar to the endogenous hormone. Synthesized in and secreted by the hypothalamus, gonadorelin binds to transmembrane LHRH receptors on pituitary gonadotrophic cells, thereby stimulating synthesis and secretion of gonadotropins. Continuous administration of gonadorelin desensitizes the gonadotrophic cells, a negative feedback effect. This agent can be used in treatment of hypothalamic amenorrhea and evaluation of hypothalamic/pituitary function.;

UNII : 9O7312W37G;

CAS number : 33515-09-2;

Drug name : Lutrepulse; Lutrelef; Luforan; Factrel; Relisorm L; Fertiral; Relefact LH-RH; Cryptocur; HRF; Kryptocur; Stimu-LH; Lutrefact; GnRH;

Molecule name : Abbott-41070;

Chemical formula : C55H75N17O13;

Details

Origin ID

C613;

UMLS CUI

C3146229;

False automatic mappings
- LHRH (1-10) [MeSH concept]
- LHRH (1-10) [MeSH Supplementary Concept]
- LHRH (1-5) [MeSH concept]
- LHRH (1-5) [MeSH Supplementary Concept]
- LHRH (1-6) [MeSH concept]
- LHRH (1-6) [MeSH Supplementary Concept]
- LHRH (1-9) [MeSH concept]
- LHRH (1-9) [MeSH Supplementary Concept]
- LHRH (2-10) [MeSH concept]
- LHRH (2-10) [MeSH Supplementary Concept]
- gonadorelin(6-D-Phe) [MeSH concept]
- gonadorelin(6-D-Phe) [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Luteotropin-releasing factor [FMA entity]
- gonadotropin-releasing hormone [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- gonadorelin [ATC Code]
Validated automatic mappings to NTBT
- Gonadorelin [SMS substance]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Gonadorelin Acetate [NCIt concept]
- Gonadorelin Hydrochloride [NCIt concept]
is_component_of_chemotherapy_regimen
- Cyproterone/Luteinizing Hormone-Releasing Factor [NCIt concept]
is_free_acid_or_base_form_of
- Gonadorelin Acetate [NCIt concept]
- Gonadorelin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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