Recombinant Luteinizing Hormone

Preferred Label : Recombinant Luteinizing Hormone;

NCIt synonyms : Interstitial Cell-Stimulating Hormone; Leuteinizing Hormone; Therapeutic LH; Therapeutic Luteinizing Hormone; Recombinant LH;

NCIt related terms : lutropin; LH; LUTEINIZING HORMONE;

NCIt definition : Any recombinant form of the endogenously produced heterodimer glycoprotein luteinizing hormone (LH) normally made by the anterior pituitary gland, that can be used for the treatment of LH deficiency. Upon administration, recombinant LH mimics the biological activity of endogenous LH. In females, this triggers ovulation and the development of the corpus luteum. In males, LH stimulates Leydig cells to produce testosterone.;

Alternative definition : NCI-GLOSS: A hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their eggs and to make hormones that get the uterus ready for a fertilized egg to be implanted. In males, it acts on the testes to cause cells to grow and make testosterone.;

UNII : 8XA4VN1LH4;

CAS number : 9002-67-9;

Codes from synonyms : CDR0000643020; CDR0000643021; CDR0000643022; CDR0000643019;

Details

Origin ID

C612;

UMLS CUI

C1704298;

Automatic exact mappings (from CISMeF team)
- Lutropin [LOINC Challenge]
- Procollagen-lysine, 2-oxoglutarate 5-dioxygenase [OMIM gene]
- big luteinizing hormone [MeSH concept]
- big luteinizing hormone [MeSH Supplementary Concept]
- lateral hypothalamic area [UBERON concept]
- luteinizing hormone subunit beta [HGNC gene]
Currated CISMeF NLP mapping
- Interstitial cell-stimulating hormone [MedDRA LLT]
- Luteinizing hormone [ICHI extension code]
- Luteinizing hormone [FMA entity]
- Lutropin [FMA entity]
- Lutropin [LOINC component]
- Pituitary luteinizing hormone (substance) [SNOMED CT concept]
- luteinizing hormone [Substance BNPC]
- luteinizing hormone [MeSH Descriptor]
- luteinizing hormone [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Luteinising hormone [SMS substance]
- Luteinizing hormone [ICD-11 Extension code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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