NCIt definition : Human NANOG wild-type allele is located in the vicinity of 12p13.31 and is approximately
7 kb in length. This allele, which encodes homeobox protein NANOG, plays a role in
both the modulation of transcription by RNA polymerase II and the establishment of
embryonic stem cell pleuripotency.;
NCIt note : The NANOG gene product binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'
(GeneCards).;