Demineralized Bone Matrix

Preferred Label : Demineralized Bone Matrix;

NCIt synonyms : DBM;

NCIt definition : Demineralized allograft bone with osteoinductive activity. Demineralized bone matrices are prepared by acid extraction of allograft bone, resulting in loss of most of the mineralized component but retention of collagen and noncollagenous proteins, including growth factors. The efficacy of a demineralized bone matrix (DBM) as a bone-graft substitute or extender may be related to the total amount of bone morphogenetic protein (BMP) present, and the ratios of the different BMPs present. BMPs belong to the transforming growth factor (TGF) superfamily of proteins.;

Details

Origin ID

C61085;

UMLS CUI

C1832069;

Currated CISMeF NLP mapping
- demineralized bone matrix [Radlex concept]
False automatic mappings
- Leukemia, chronic lymphocytic, susceptibility to, 2 [OMIM Phenotype]
Semantic type(s)
- Biomedical or Dental Material [UMLS semantic type]
UMLS correspondences (same concept)
- demineralized bone matrix [Radlex concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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