Isoniazid - CISMeF

Preferred Label : Isoniazid;

NCIt synonyms : Isonicotinic Acid Hydrazide; Isonicotinyl Hydrazine;

NCIt definition : A synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due to decreased bacterial wall penetration. (NCI04);

UNII : V83O1VOZ8L;

InChIKey : QRXWMOHMRWLFEY-UHFFFAOYSA-N;

CAS number : 54-85-3;

Chemical formula : C6H7N3O;

NSC code : 9659;

ChEBI ID : CHEBI:6030;

Codes from synonyms : NSC0009659;

Details

Origin ID

C600;

UMLS CUI

C0022209;

See also inter- (CISMeF)
- Product containing isoniazid (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Isoniazid [ICD-11 Extension code]
- Isoniazid [LOINC component]
- Isoniazid (substance) [SNOMED CT concept]
- Isonicotinic acid hydrazide [ICD-11 Extension code]
- Product containing isoniazid (medicinal product) [SNOMED CT concept]
- isoniazid [ATC Code]
- isoniazid [Substance BNPC]
- isoniazid [International Nonproprietary Name]
- isoniazid [MeSH concept]
- isoniazid [MeSH Descriptor]
- isoniazid [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- BCG/Isoniazid [NCIt concept]

Keyword's position in hierarchy(ies) :

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