Preferred Label : Stage IVA Hypopharyngeal Carcinoma AJCC v7;
NCIt synonyms : Stage IVA Carcinoma of the Hypopharynx; Stage IVA Carcinoma of Hypopharynx; Stage IVA Hypopharynx Carcinoma; Stage IVA Hypopharyngeal Carcinoma;
NCIt related terms : Stage IVA Hypopharyngeal Throat Cancer; stage IVA hypopharyngeal cancer;
NCIt definition : Stage IVA includes: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3,
N2, M0); (T4a, N2, M0). T4a: Tumor with moderately advanced local disease. Tumor invades
the thyroid/cricoid cartilage, hyoid bone, thyroid gland, or central compartment soft
tissue. Central compartment soft tissue includes prelaryngeal strap muscles and subcutaneous
fat. T1: Tumor limited to one subsite of hypopharynx and/or 2 cm or less in greatest
dimension. T2: Tumor invades more than one subsite of the hypopharynx or an adjacent
site, or measures more than 2 cm but not more than 4 cm in greatest diameter without
fixation of hemilarynx. T3: Tumor measuring more than 4 cm in greatest dimension or
tumor with fixation of hemilarynx or extension to esophagus. N0: No regional lymph
node metastasis. N1: Metastasis in a single ipsilateral lymph node, 3 cm or less in
greatest dimension. N2: Tumor with metastasis in a single ipsilateral lymph node,
more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral
lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral
lymph nodes, none more than 6 cm in greatest dimension. M0: No distant metastasis.
(AJCC 7th ed.);
Alternative definition : NCI-GLOSS: Stage IV hypopharyngeal cancer is divided into stages IVA, IVB, and IVC.
In stage IVA, the tumor is (1) any size and has spread to nearby soft tissue, connective
tissue, the thyroid, or the esophagus; cancer may be found either in one lymph node
on the same side of the neck (the lymph node is 3 centimeters or smaller) or in one
or more lymph nodes anywhere in the neck (all of these lymph nodes are 6 centimeters
or smaller); or (2) in only one area of the hypopharynx, is 2 centimeters or smaller,
and has also spread to one or more lymph nodes anywhere in the neck (all of these
lymph nodes are 6 centimeters or smaller); or (3) in more than one area of the hypopharynx,
is in nearby tissues, or is larger than 2 centimeters but not larger than 4 centimeters
and has not spread to the larynx; cancer has spread to one or more lymph nodes anywhere
in the neck (all of these lymph nodes are 6 centimeters or smaller); or (4) larger
than 4 centimeters or has spread to the larynx; cancer has also spread to one or more
lymph nodes anywhere in the neck (all of these lymph nodes are 6 centimeters or smaller).;
Neoplastic status : Malignant;
Codes from synonyms : CDR0000430497;
Origin ID : C5992;
UMLS CUI : C1336340;
Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
