Major Salivary Gland Carcinoma ex Pleomorphic Adenoma

Preferred Label : Major Salivary Gland Carcinoma ex Pleomorphic Adenoma;

NCIt synonyms : Carcinoma ex Pleomorphic Adenoma of the Major Salivary Gland; Carcinoma ex Pleomorphic Adenoma of Major Salivary Gland;

NCIt definition : A carcinoma that arises from a pleomorphic adenoma in the major salivary glands. It usually originates in the parotid gland. Patients usually present with a history of a long-standing tumor mass which grew rapidly in the past few months. Patients with non-invasive or minimally invasive carcinoma have an excellent prognosis. In cases where there is invasion of the surrounding tissues, the clinical course is aggressive.;

Neoplastic status : Malignant;

Details

Origin ID

C5975;

UMLS CUI

C1334550;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Glial Cell [NCIt concept]
Disease may have findings
- Cartilaginous Component Present [NCIt concept]
- Lipomatous Component Present [NCIt concept]
- Myxoid Stroma Formation [NCIt concept]
- Osseous Component Present [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Major Salivary Gland [NCIt concept]
- Salivary Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Malignant Epithelial Cell Population [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_associated_disease
- Pleomorphic Adenoma [NCIt concept]
- Salivary Gland Pleomorphic Adenoma [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mesenchymal Component Present [NCIt concept]
- Mixed Cellular Population [NCIt concept]
- Secondary Lesion [NCIt concept]
disease_has_normal_cell_origin
- Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Myoepithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Major Salivary Gland [NCIt concept]
- Salivary Gland [NCIt concept]
disease_may_have_cytogenetic_abnormality
- HMGA2 Gene Rearrangement [NCIt concept]
- PLAG1 Gene Rearrangement [NCIt concept]
disease_may_have_molecular_abnormality
- EGFR Gene Amplification [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- MYC Gene Amplification [NCIt concept]
- PIK3CA Gene Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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