Ionomycin - CISMeF

Preferred Label : Ionomycin;

NCIt definition : A polyether antibiotic isolated from Streptomyces conglobatus sp. nov. Trejo with antineoplastic activity. Ionomycin is a calcium ionophore that increases intracellular Ca levels, possibly relating to endonuclease activation of lymphocytes and decreased ratio of Bcl-2 to Bax and ultimately apoptosis. In addition, this agent is used to investigate the role of intracellular calcium in cellular processes. (NCI);

UNII : 54V905V6AT;

CAS number : 56092-81-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 56092-81-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

ChEBI ID : CHEBI:63954;

Codes from synonyms : CDR0000045998;

Details

Origin ID

C596;

UMLS CUI

C0022020;

Currated CISMeF NLP mapping
- Ionomycin (substance) [SNOMED CT concept]
- ionomycin [MeSH Descriptor]
- ionomycin [MeSH concept]
- ionomycin [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ionomycin (substance) [SNOMED CT concept]
- ionomycin [MeSH concept]
- ionomycin [MeSH Descriptor]
- ionomycin [SNOMED Notion]
chemical_or_drug_has_physiologic_effect
- Ion Transport Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Bryostatin 1/Interleukin-2/Ionomycin [NCIt concept]

Keyword's position in hierarchy(ies) :

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