Major Salivary Gland Adenoid Cystic Carcinoma

Preferred Label : Major Salivary Gland Adenoid Cystic Carcinoma;

NCIt synonyms : Adenoid Cystic Carcinoma of the Major Salivary Gland; Adenoid Cystic Carcinoma of Major Salivary Gland;

NCIt related terms : Major Salivary Gland Adenoid Cystic Cancer;

NCIt definition : An aggressive carcinoma that arises from the major salivary glands. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues.;

Neoplastic status : Malignant;

Details

Origin ID

C5905;

UMLS CUI

C1334548;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Cribriform Pattern [NCIt concept]
- Pain [NCIt concept]
- Slow Growing Mass [NCIt concept]
- Solid Growth Pattern [NCIt concept]
- Tubular Pattern [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Major Salivary Gland [NCIt concept]
- Salivary Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Perineural Invasion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Major Salivary Gland [NCIt concept]
- Salivary Gland [NCIt concept]
disease_mapped_to_gene
- MYB/NFIB Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(6;9)(q22-23;p23-24) [NCIt concept]
disease_may_have_molecular_abnormality
- Loss of E-cadherin Expression [NCIt concept]

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