Preferred Label : Hydroxamic Acids;
NCIt definition : A group of weak acids with the general chemical formula RC( O)N(R')OH and antineoplastic
and antimicrobial activities. Hydroxamic acids covalently bind to the zinc(II) ion
in the active sites of matrix metalloproteinases (MMP), thereby inhibiting the action
of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor
growth and invasion, and metastasis. (NCI04);
ChEBI ID : CHEBI:24650;
Origin ID : C556;
UMLS CUI : C0020314;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
