Low Grade Prostatic Intraepithelial Neoplasia

Preferred Label : Low Grade Prostatic Intraepithelial Neoplasia;

NCIt synonyms : Low-Grade Intraepithelial Neoplasia of the Prostate; Grade I PIN; Grade 1 PIN; PIN-1; Grade 1 Prostatic Intraepithelial Neoplasia; Low-Grade PIN; Grade I Prostatic Intraepithelial Neoplasia; Low-Grade Intraepithelial Neoplasia of Prostate; Low-Grade Prostatic Intraepithelial Neoplasia;

NCIt definition : Prostatic intraepithelial neoplasia characterized by the proliferation of secretory cells with irregular spacing in the ducts and acini. Although some proliferating epithelial cells may contain prominent nucleoli, the cytologic atypia and architectural growth patterns that are seen in the high grade prostatic intraepithelial neoplasia are absent. The presence of low grade prostatic intraepithelial neoplasia in needle biopsy is not a risk factor for the subsequent detection of carcinoma on repeat biopsy.;

Neoplastic status : Undetermined;

Details

Origin ID

C5542;

UMLS CUI

C1168328;

CISMeF manual mappings
- Low grade prostatic intraepithelial neoplasia (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Low grade prostatic intraepithelial neoplasia [MedDRA LLT]
Disease excludes abnormal cell
- Dysplastic Squamous Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Low grade prostatic intraepithelial neoplasia [MedDRA LLT]
- Low grade prostatic intraepithelial neoplasia (disorder) [SNOMED CT concept]
- Prostatic intraepithelial neoplasia low grade (disorder) [SNOMED CT concept]
disease_excludes_finding
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Glandular Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Mild Dysplasia [NCIt concept]
disease_has_grade
- Low Grade [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Prostate Gland [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 10 [NCIt concept]
- Gain of Chromosome 12 [NCIt concept]
- Gain of Chromosome 7 [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Gain of Chromosome Y [NCIt concept]
- Loss of Chromosome 10q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
disease_may_have_molecular_abnormality
- TP53 Gene Inactivation [NCIt concept]

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