NCIt definition : Alteration of the disposition and/or effect of a drug, owing to the presence of another
factor such as a second drug, or food.;
Alternative definition : NCI-GLOSS: A change in the way a drug acts in the body when taken with certain other
drugs, herbals, or foods, or when taken with certain medical conditions. Drug interactions
may cause the drug to be more or less effective, or cause effects on the body that
are not expected.;