Invasive Breast Lobular Carcinoma, Signet Ring Variant

Preferred Label : Invasive Breast Lobular Carcinoma, Signet Ring Variant;

NCIt synonyms : Signet Ring Cell Lobular Breast Carcinoma; Invasive Lobular Breast Carcinoma, Signet Ring Variant; Invasive Breast Lobular Carcinoma, Signet-Ring Variant;

NCIt definition : An invasive lobular carcinoma characterized by the presence of malignant epithelial cells with large intracytoplasmic lumina that cause displacement of the nuclei towards one pole of the cells.;

Neoplastic status : Malignant;

Details

Origin ID

C54691;

UMLS CUI

C1883029;

Disease excludes abnormal cell
- Ductal Carcinoma Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Breast Lump [NCIt concept]
- Pain [NCIt concept]
- Single-File Linear Pattern [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intestinal Metaplasia [NCIt concept]
- Mixed Cellular Population [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Lobular Carcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Signet Ring Adenocarcinoma Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Terminal Ductal Lobular Unit Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
- Terminal Ductal Lobular Unit [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
disease_mapped_to_gene
- CDH1 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 16q [NCIt concept]
disease_may_have_molecular_abnormality
- CDH1 Gene Inactivation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- PIK3CA Gene Mutation [NCIt concept]

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