NCIt related terms : IMMUNOFIXATION ELECTROPHORESIS;
NCIt definition : An enhancement of immunoelectrophoresis in which a series of post-electrophoretic
gel slabs are layered with cellulose-acetate gels saturated with specific antibodies.
The resulting antigen-antibody complexes fixed on the second gel may then be stained,
allowing sensitive and specific qualitative visual identification of paraproteins
by electrophoretic position. It can be used to identify specific proteins in the blood
or urine. It has greatest application in the identification and monitoring of monoclonal
proteins that are produced in conditions like Waldenstom's macroglobulinaemia and
multiple myeloma.;
Alternative definition : CDISC: An enhancement of immunoelectrophoresis in which a series of post-electrophoretic
gel slabs are layered with cellulose-acetate gels saturated with specific antibodies.
The resulting antigen-antibody complexes fixed on the second gel may then be stained,
allowing sensitive and specific qualitative visual identification of proteins by electrophoretic
position.;
Currated CISMeF NLP mapping