Preferred Label : Altretamine;
NCIt synonyms : N,N,N',N',N,N-hexamethyl-1,3,5-triazine-2,4,6-triamine; Hexamethylamine; Hexaloids; N,n,n',NN-hexamethyl-1,3,5,-triazine-2,4,6,-triamine; HXM; HMM; Hexamethylmelamine;
NCIt related terms : ENT 50852; s-Triazine, 2,4,6-tris(dimethylamino)-; Hemel; Hexastat; 2,4,6-Tris(dimethylamino)-s-triazine;
NCIt definition : A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent
triethylenemelamin with antineoplastic activity. Although the precise mechanism by
which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine
may produce reactive intermediates which covalently bind to DNA, resulting in DNA
damage. (NCI04);
Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating
agents.;
UNII : Q8BIH59O7H;
InChIKey : UUVWYPNAQBNQJQ-UHFFFAOYSA-N;
CAS number : 645-05-6;
Drug name : Hexinawas; Hexastat; Hexalen;
Molecule name : RB-1515; ENT-50852; WR-95704;
Chemical formula : C9H18N6;
NSC code : 13875;
ChEBI ID : CHEBI:24564;
Codes from synonyms : NSC0013875; CDR0000045215; 23;
Origin ID : C544;
UMLS CUI : C0019453;
Automatic exact mappings (from CISMeF team)
- False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
