TUSC2 wt Allele

Preferred Label : TUSC2 wt Allele;

NCIt synonyms : PDAP2; PAP; FUS1; C3orf11; Tumor Suppressor Candidate 2 wt Allele; PDAP2 wt Allele; LGCC;

NCIt definition : Human TUSC2 wild-type allele is located in the vicinity of 3p21.3 and is approximately 3 kb in length. This allele, which encodes tumor suppressor candidate 2 protein, plays a putative role in cell cycle arrest and the induction of apoptosis. Loss of TUSC2 gene function is associated with several types of lung cancer.;

GenBank Accession Number : NM_007275;

Details

Origin ID

C54391;

UMLS CUI

C1705531;

OMIM relation
- Tumor suppressor candidate 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Lung Neoplasm [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p21.3 [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Inhibition of Cancer Cell Growth [NCIt concept]
- Tumor Suppression [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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