Nasopharyngeal Basaloid Squamous Cell Carcinoma

Preferred Label : Nasopharyngeal Basaloid Squamous Cell Carcinoma;

NCIt synonyms : Nasopharyngeal Basaloid Carcinoma;

NCIt definition : An aggressive variant of squamous cell carcinoma that arises from the nasopharynx. It is characterized by the presence of small malignant cells with hyperchromatic nuclei and scant amount of cytoplasm forming lobules with peripheral palisading. Comedonecrosis may be present.;

Neoplastic status : Malignant;

Details

Origin ID

C54360;

UMLS CUI

C1711232;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Headache [NCIt concept]
- Nasal Obstruction [NCIt concept]
- Neck Mass [NCIt concept]
- Rhinorrhea [NCIt concept]
- Tinnitus [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Nasopharynx [NCIt concept]
- Neck [NCIt concept]
- Pharynx [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Hyperchromatic Epithelial Cell [NCIt concept]
- Malignant Hyperchromatic Squamous Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Monomorphic Cellular Infiltrate [NCIt concept]
- Peripheral Nuclear Palisading [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Nasopharynx Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Nasopharynx [NCIt concept]
- Neck [NCIt concept]
- Pharynx [NCIt concept]
- Throat [NCIt concept]
disease_mapped_to_gene
- HLA-A Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 11q [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 14q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
- Loss of Chromosome 9q [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Protein Overexpression [NCIt concept]
- RASSF1A Gene Inactivation [NCIt concept]

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