Laryngeal Acantholytic Squamous Cell Carcinoma

Preferred Label : Laryngeal Acantholytic Squamous Cell Carcinoma;

NCIt definition : A rare variant of squamous cell carcinoma that arises from the larynx. It is characterized by acantholysis of the tumor cells that results in the formation of pseudolumina resembling glandular structures.;

Neoplastic status : Malignant;

Details

Origin ID

C54337;

UMLS CUI

C1708648;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Larynx [NCIt concept]
- Neck [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Malignant Acantholytic Squamous Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Acantholysis [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Pseudoglandular Pattern [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Laryngeal Epithelium [NCIt concept]
- Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Larynx [NCIt concept]
- Neck [NCIt concept]
- Throat [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 11q13 [NCIt concept]
- Gain of Chromosome 14 [NCIt concept]
- Gain of Chromosome 17q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Gain of Chromosome 3q [NCIt concept]
- Gain of Chromosome 5p [NCIt concept]
- Gain of Chromosome 7p [NCIt concept]
- Gain of Chromosome 7q [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Gain of Chromosome 9q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
disease_may_have_molecular_abnormality
- EGFR Protein Overexpression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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