MSLN wt Allele

Preferred Label : MSLN wt Allele;

NCIt synonyms : CAK1; SMR; Mesothelin wt Allele; MPF; SMRP;

NCIt definition : Human MSLN wild-type allele is located in the vicinity of 16p13.3 and is approximately 8 kb in length. This allele, which encodes mesothelin protein, may play a role in the mediation of cellular adhesion.;

NCIt note : This MSLN gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Antibodies against the MSLN gene product are detected in patients with mesothelioma and ovarian cancer. (Entrez Gene and SwissProt);

GenBank Accession Number : NM_005823;

Details

Origin ID

C54329;

UMLS CUI

C1704868;

OMIM relation
- Mesothelin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 16p13.3 [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Immune Response Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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