NCIt synonyms : MAGE3; MGC14613; MAGE-3 Gene; Melanoma Antigen Family A, 3 wt Allele; HYPD; MAGEA6; HIP8;
NCIt related terms : MAGE-3;
NCIt definition : Human MAGEA3 wild-type allele is located in the vicinity of Xq28 and is approximately
4 kb in length. This allele, which encodes melanoma-associated antigen 3 protein,
plays a role in the regulation of tumor cell recognition by killer T lymphocytes and
may be involved in embryonic development.;
NCIt note : The MAGEA3 gene is a member of the MAGEA gene family. Genes in this family are expressed
in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma,
lung carcinoma and breast carcinoma, but not in normal tissues except for testes and
placenta or in kidney tumors, leukemias and lymphomas. (Entrez Gene and SwissProt);