Odontogenic Keratocyst

Preferred Label : Odontogenic Keratocyst;

NCIt synonyms : OKC; Keratocystic Odontogenic Tumor;

NCIt definition : A developmental cyst that arises from remnants of the dental lamina. It is characterized by a thin, regular lining of parakeratinized stratified squamous epithelium with palisading hyperchromatic basal cells. It occurs most frequently in the mandible. Most lesions present as painless radiolucencies and are found incidentally during radiographical examination for other reasons. Treatment is most often by enucleation, or by surgical resection for large lesions. Recurrences were more frequent in the past but are dramatically reduced with meticulous treatment. (WHO 2017);

Details

Origin ID

C54302;

UMLS CUI

C1708604;

Automatic exact mappings (from CISMeF team)
- Keratocystic odontogenic tumor [ORDO Disease]
- Odontogenic keratocyst [MedDRA LLT]
- Odontogenic keratocyst (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Odontogenic keratocyst (morphologic abnormality) [SNOMED CT concept]
- Odontogenic keratocysts of the jaw [HPO term]
- Primordial cyst (disorder) [SNOMED CT concept]
- keratocystic odontogenic neoplasm [Disease (Nov.)]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Odontogenic keratocysts of the jaw [HPO term]
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- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
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- PTCH1 Gene Mutation [NCIt concept]
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- Primary Intraosseous Carcinoma, Not Otherwise Specified, Derived from Odontogenic Keratocyst [NCIt concept]

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