NOP53 wt Allele

Preferred Label : NOP53 wt Allele;

NCIt synonyms : GLTSCR2; PICT1; PICT-1; Glioma Tumor Suppressor Candidate Region Gene 2 Gene; NOP53 Ribosome Biogenesis Factor wt Allele; GLTSCR2 wt Allele;

NCIt definition : Human NOP53 wild-type allele is located in the vicinity of 19q13.3 and is approximately 12 kb in length. This allele, which encodes ribosome biogenesis protein NOP53, is involved in tumor suppression, the cellular response to stress and ribosome maturation.;

NCIt note : The GLTSCR2 gene is a putative glioma suppressor gene. In a study utilizing a small number of malignant peripheral nerve sheath tumors, the GLTSCR2 gene was determined to be frequently lost in comparison to schwannomas.;

GenBank Accession Number : NM_015710;

Details

Origin ID

C54279;

UMLS CUI

C1708126;

OMIM relation
- Ribosome biogenesis factor nop53 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 19: 52940620-52952127 [NCIt concept]
gene_in_chromosomal_location
- 19q13.3 [NCIt concept]
gene_plays_role_in_process
- Cellular Stress Response [NCIt concept]
- RNA Binding [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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