NCIt synonyms : Columnar Cell Lesion of Breast; Columnar Cell Lesion of the Breast;
NCIt definition : A morphologic spectrum of lesions that arise in the terminal ductal lobular units
of the breast parenchyma. These lesions are characterized by the presence of columnar
epithelial cells that line dilated terminal ductal lobular units. Cytological and
architectural atypia may be absent or minimal, or significant enough to raise the
possibility of atypical ductal hyperplasia or ductal carcinoma in situ. Columnar cell
lesions are frequently found in breast biopsies but their biologic significance is
not known.;