Malignant Gastrointestinal Stromal Tumor

Preferred Label : Malignant Gastrointestinal Stromal Tumor;

NCIt synonyms : Probably Malignant Gastrointestinal Stromal Tumor;

NCIt related terms : GIST, Malignant; Gastrointestinal stromal tumor, malignant;

NCIt definition : A gastrointestinal stromal tumor that is characterized by large size (diameter greater than 10 cm for gastric localization and greater than 5 cm for intestinal localization) or more than 5 mitotic figures per 50 high power fields.;

Alternative definition : CDISC: A malignant neoplasm arising from specialized smooth muscle cells (i.e., interstitial cells of Cajal) in the tunica muscularis or myenteric plexus. (INHAND);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL497447;

ICD-O code : 8936/3;

Details

Origin ID

C53999;

UMLS CUI

C3179349;

Automatic exact mappings (from CISMeF team)
- Gastrointestinal stromal sarcoma (morphologic abnormality) [SNOMED CT concept]
- Gastrointestinal stromal tumour [ICD-11 Extension code]
Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Lesion with Diameter Greater than 10 cm [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Gastrointestinal stromal sarcoma (morphologic abnormality) [SNOMED CT concept]
- gastrointestinal stromal sarcoma [MeSH concept]
Validated automatic mappings to NTBT
- gastrointestinal stromal tumor [Disease (Nov.)]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Sarcoma Baseline Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- More than 5 Mitoses per 50 HPF [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Interstitial Cell of Cajal [NCIt concept]
- Stromal Cell [NCIt concept]
disease_has_normal_tissue_origin
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_mapped_to_gene
- KIT Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 14 [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 22 [NCIt concept]
disease_may_have_molecular_abnormality
- KIT Gene Mutation [NCIt concept]
- PDGFRA Gene Mutation [NCIt concept]

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