ITGB5 wt Allele

Preferred Label : ITGB5 wt Allele;

NCIt synonyms : Integrin, Beta 5 wt Allele; Integrin, Beta-5 Gene;

NCIt definition : Human ITGB5 wild-type allele is located in the vicinity of 3q21.2 and is approximately 124 kb in length. This allele, which encodes integrin beta-5 protein, is involved in cell-extracellular adhesion, intercellular adhesion and receptor-mediated signal transduction. Variant alleles are associated with several cancers such as glial tumors and gastric carcinomas.;

GenBank Accession Number : NM_002213;

Details

Origin ID

C53960;

UMLS CUI

C1708458;

OMIM relation
- Integrin, beta-5 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q21.2 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients