Preferred Label : Saponin-Cholesterol-Phospholipid Adjuvant;
NCIt synonyms : Saponin Cholesterol Phospholipid Adjuvant;
NCIt definition : An adjuvant comprised of saponin, derived from the bark of Quillaia saponaria Molina,
cholesterol and phospholipid with antigen-delivery and immunostimulatory activities.
This saponin-based adjuvant in combination with various antigens, including those
for human papilloma virus (HPV), hepatitis C virus (HCV), and the human cancer antigen
NY-ESO-1, may result in potent antibody, CD4 T-helper-cell, and CD8 cytotoxic T-cell
responses against the targeted antigen. In addition, this agent may reduce the amount
of antigen necessary to induce an efficient immune response in the host.;
Drug name : Iscomatrix;
Origin ID : C53436;
UMLS CUI : C1710013;
Semantic type(s)
- concept_is_in_subset
