Preferred Label : Yttrium Y-90-DOTA-Girentuximab;
NCIt synonyms : Yttrium-90 DOTA Conjugated Chimeric MoAb G250; Yttrium Y 90-DOTA-Chimeric Monoclonal Antibody cG250; 90Y-DOTA-cG250; Yttrium Y 90 DOTA Chimeric Monoclonal Antibody cG250;
NCIt definition : A radioimmunoconjugate comprised of the chimeric monoclonal antibody cG250 conjugated
with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic
acid (DOTA) and labeled with the beta-emitting radioisotope yttrium 90. The antibody
moiety of yttrium 90 DOTA chimeric monoclonal antibody cG250 binds to renal cell carcinoma
cells expressing the G250 antigen, thereby selectively delivering a cytotoxic dose
of beta radiation.;
Origin ID : C53409;
UMLS CUI : C1710703;
Semantic type(s)
- concept_is_in_subset
- has_target
