NCIt definition : The alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor
with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2,
a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells;
inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of
tumor cell growth, and tumor regression.;
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer. Brivanib alaninate
may prevent the growth of new blood vessels that tumors need to grow and may kill
cancer cells. It is a type of vascular endothelial growth factor receptor 2 inhibitor
and a type of antiangiogenesis agent.;
UNII : U2Y5OFN795;
InChIKey : LTEJRLHKIYCEOX-OCCSQVGLSA-N;
CAS number : 649735-63-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 649735-63-7
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;