NCIt synonyms : FLJ21080; ZMYND1; SET and MYND Domain Containing 3 wt Allele; ZNFN3A1; SMYD3; Zinc Finger Protein Subfamily 3A (MYND Domain Containing) 1 Gene;
NCIt definition : Human SMYD3 wild-type allele is located in the vicinity of 1q44 and is approximately
758 kb in length. This allele, which encodes SET and MYND domain-containing protein
3, plays a role in both the methylation of histones and the regulation of transcription
by RNA polymerase II.;
NCIt note : The SMYD3 gene product is a histone methyltransferase, specifically methylating Lys-4
of histone H3, inducing di- and tri-methylation, but not monomethylation (GeneCards);
OMIM relation