NFIB wt Allele

Preferred Label : NFIB wt Allele;

NCIt synonyms : Nuclear Factor I/B wt Allele; NFIB3; NFI-RED; NF-IB; NFIB2;

NCIt definition : Human NFIB wild-type allele is located in the vicinity of 9p24.1 and is approximately 233 kb in length. This allele, which encodes nuclear factor 1 B-type protein, is involved in both the modulation of transcription by RNA polymerase II and the activation of DNA replication.;

NCIt note : The NFIB gene product recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2 (GeneCards).;

GenBank Accession Number : NM_005596;

Details

Origin ID

C53093;

UMLS CUI

C1705926;

OMIM relation
- Nuclear factor I/b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Adenoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 9: 14303719-14077373 [NCIt concept]
gene_in_chromosomal_location
- 9p24.1 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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