NFIA wt Allele

Preferred Label : NFIA wt Allele;

NCIt synonyms : NF-IA; NFIA; NFI-L; Nuclear Factor I/A wt Allele;

NCIt definition : Human NFIA wild-type allele is located within 1p31.3-p31.2 and is approximately 598 kb in length. This allele, which encodes nuclear factor 1 A-type protein, plays a role in both the modulation of transcription by RNA polymerase II and the activation of DNA replication.;

NCIt note : The NFIA gene product recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2 (GeneCards).;

GenBank Accession Number : NM_005595;

Details

Origin ID

C53092;

UMLS CUI

C1705936;

OMIM relation
- Nuclear factor I/a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 61260314-61634057 [NCIt concept]
gene_in_chromosomal_location
- 1p31.3-p31.2 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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