MYB wt Allele - CISMeF

Preferred Label : MYB wt Allele;

NCIt synonyms : c-MYB; Avian Myeloblastosis Viral Oncogene Homolog Gene; MYB; Cmyb; MYB Protooncogene, Transcription Factor Gene; v-Myb Avian Myeloblastosis Viral Oncogene Homolog Gene; MYB Proto-Oncogene, Transcription Factor wt Allele; efg; V-Myb Myeloblastosis Viral Oncogene Homolog Gene; v-MYB Myeloblastosis Viral Oncogene Homolog (Avian) Gene;

NCIt definition : Human MYB wild-type allele is located within 6q22-q23 and is approximately 38 kb in length. This allele, which encodes Myb proto-oncogene protein, plays a role in both the modulation of transcription by RNA polymerase II and differentiation of hematopoietic progenitor cells.;

NCIt note : The MYB gene product is a DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3' (GeneCards).;

GenBank Accession Number : NM_005375;

Details

Origin ID

C53082;

UMLS CUI

C1705286;

OMIM relation
- Myb protooncogene, transcription factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- MYB Gene Amplification [NCIt concept]
gene_in_chromosomal_location
- 6q22-q23 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Angiocentric Glioma [NCIt concept]
- Diffuse Astrocytoma, MYB-Altered [NCIt concept]
gene_is_element_in_pathway
- IL2/PI3K Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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