NKX3-1 wt Allele

Preferred Label : NKX3-1 wt Allele;

NCIt synonyms : NKX3.1; NKX3-1; NKX3A; NK3 Transcription Factor Related, Locus 1 (Drosophila) wt Allele;

NCIt definition : Human NKX3-1 wild-type allele is located in the vicinity of 8p21 and is approximately 4 kb in length. This allele, which encodes homeobox protein Nkx-3.1, plays a role in the suppression of transcription by RNA polymerase II, the proliferation of glandular epithelium and the development of ducts in the prostate.;

NCIt note : The NKX3-1 gene product binds to the consensus sequence 5'-TAAGT[AG]-3' (GeneCards).;

GenBank Accession Number : NM_006167;

Details

Origin ID

C53019;

UMLS CUI

C1705029;

OMIM relation
- Nk3 homeobox 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p21 [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- DNA Binding [NCIt concept]
- Developmental Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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