ETV1 wt Allele

Preferred Label : ETV1 wt Allele;

NCIt synonyms : ETS Variant 1 Gene; ETV1; ER81; ETS Variant Gene 1; ETS Variant Transcription Factor 1 wt Allele;

NCIt definition : Human ETV1 wild-type allele is located in the vicinity of 7p21.3 and is approximately 98 kb in length. This allele, which encodes ETS translocation variant 1 protein, plays a role in the activation of transcription by RNA polymerase II. Ewing sarcoma is linked to the chromosomal translocation t(7;22)(p22;q12) of this gene with the EWSR1 gene.;

NCIt note : The product of the ETV1 gene binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (GeneCards).;

GenBank Accession Number : NM_004956;

Details

Origin ID

C52868;

UMLS CUI

C1705693;

OMIM relation
- Ets variant transcription factor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 7: 13803555-13708330 [NCIt concept]
gene_in_chromosomal_location
- 7p22 [NCIt concept]
gene_is_element_in_pathway
- p38 MAPK/MAPKAP Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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