ETS1 wt Allele

Preferred Label : ETS1 wt Allele;

NCIt synonyms : EWSR2; ETS1; p54; ETS; ETS1 Proto-Oncogene; c-ets-1; ETS Proto-Oncogene 1, Transcription Factor wt Allele; ETS-1; v-ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1 Gene; v-ETS Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) Gene;

NCIt definition : Human ETS1 wild-type allele is located in the vicinity of 11q23 and is approximately 64 kb in length. This allele, which encodes protein C-ets-1, plays a role in the modulation of transcription by RNA polymerase II. Chromosomal aberrations leading to rearrangement or elevated expression of the gene are a factor in a variety of leukemias.;

GenBank Accession Number : NM_005238;

Details

Origin ID

C52866;

UMLS CUI

C1705691;

Automatic exact mappings (from CISMeF team)
- Dead-box helicase 6 [OMIM gene]
- ETS proto-oncogene 1, transcription factor [ORDO Gene]
- Ets protooncogene 1, transcription factor [OMIM gene]
- Fli-1 proto-oncogene, ETS transcription factor [ORDO Gene]
- Fli1 protooncogene, ets transcription factor [OMIM gene]
- ethanolamine-phosphate cytidylyltransferase activity [GO term]
- technology assessment, biomedical [MeSH Descriptor]
OMIM relation
- Ets protooncogene 1, transcription factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Acute Monocytic Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 127897371-127833873 [NCIt concept]
gene_in_chromosomal_location
- 11q23.3 [NCIt concept]
gene_is_element_in_pathway
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Dorso-Ventral Axis Formation Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- HIF-2-Alpha Transcription Factor Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Macrophage Differentiation Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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