" /> ERG wt Allele - CISMeF





Preferred Label : ERG wt Allele;

NCIt synonyms : Early Response Gene; p55; erg-3; Transcriptional Regulator ERG (Transforming Protein ERG) Gene; v-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Gene; v-ETS Erythroblastosis Virus E26 Oncogene Like (Avian) Gene; v-Ets Avian Erythroblastosis Virus E26 Oncogene Related Gene; ERG, ETS Transcription Factor Gene; v-Ets Erythroblastosis Virus E26 Oncogene Like Gene; Ets-Related Gene; ETS Transcription Factor ERG wt Allele;

NCIt definition : Human ERG wild-type allele is located in the vicinity of 21q22.3 and is approximately 280 kb in length. This allele, which encodes transcriptional regulator ERG protein, is involved in both the regulation of RNA polymerase II-directed transcription and the modification of local chromatin structure. Acute myelogenous leukemia of the subtype M2 is linked to the chromosomal translocation t(8;21)(q22;q22), which involves this gene and the EWSR1 gene. Human myeloid leukemia is linked to the chromosomal translocation t(16;21)(p11;q22) of this gene with the FUS gene.;

GenBank Accession Number : NM_004449;

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22/05/2025


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