IRAK4 wt Allele

Preferred Label : IRAK4 wt Allele;

NCIt synonyms : NY-REN-64; REN64; Interleukin 1 Receptor Associated Kinase 4 wt Allele; Interleukin-1 Receptor-Associated Kinase 4 Gene; IPD1;

NCIt definition : Human IRAK4 wild-type allele is located in the vicinity of 12q12 and is approximately 29 kb in length. This allele, which encodes interleukin-1 receptor-associated kinase 4 protein, plays a role in the modulation of both cytokine and Toll-like receptor induced signal transduction pathways.;

GenBank Accession Number : NM_016123;

Details

Origin ID

C52811;

UMLS CUI

C1704996;

OMIM relation
- Interleukin 1 receptor-associated kinase 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 12: 42439047-42468166 [NCIt concept]
gene_in_chromosomal_location
- 12q12 [NCIt concept]
gene_is_element_in_pathway
- Chagas Disease Pathway [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Immune Response Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients