NCIt synonyms : MALT Lymphoma of the Stomach; MALToma of the Stomach; Primary Gastric MALT Lymphoma; Primary MALT Lymphoma of the Stomach; Primary MALT Lymphoma of Stomach; MALToma of Stomach; Primary Gastric B-Cell MALT Lymphoma; Gastric MALT Lymphoma; MALT Lymphoma of Stomach; Gastric MALToma;
NCIt definition : A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori
infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic
(centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and
plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the
t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.;