Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

Preferred Label : Gastric Mucosa-Associated Lymphoid Tissue Lymphoma;

NCIt synonyms : MALT Lymphoma of the Stomach; MALToma of the Stomach; Primary Gastric MALT Lymphoma; Primary MALT Lymphoma of the Stomach; Primary MALT Lymphoma of Stomach; MALToma of Stomach; Primary Gastric B-Cell MALT Lymphoma; Gastric MALT Lymphoma; MALT Lymphoma of Stomach; Gastric MALToma;

NCIt definition : A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.;

Neoplastic status : Malignant;

Details

Origin ID

C5266;

UMLS CUI

C1333782;

Currated CISMeF NLP mapping
- gastric MALT lymphoma [Disease (Nov.)]
Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Lymphoepithelial Lesion [NCIt concept]
Excludes anatomical site(s)
- Lymph Node [NCIt concept]
- Skin [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Stomach [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- gastric MALT lymphoma [Disease (Nov.)]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Aggressive Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Centrocyte-Like Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Extranodal Disease [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Marginal Zone B-Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Postgerminal Center Marginal Zone B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Gut-Associated Lymphoid Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
- Marginal Zone [NCIt concept]
- Mucosa-Associated Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
- Stomach [NCIt concept]
disease_mapped_to_gene
- BIRC3/MALT1 Fusion Gene [NCIt concept]
- MALT1 Gene [NCIt concept]
disease_may_have_abnormal_cell
- Neoplastic Monocytoid B-Lymphocyte [NCIt concept]
- Neoplastic Plasma Cell [NCIt concept]
disease_may_have_associated_disease
- Hepatitis C Infection [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 18 [NCIt concept]
- Trisomy 3 [NCIt concept]
may_be_associated_disease_of_disease
- Atypical Gastric Lymphoid Hyperplasia [NCIt concept]
pathogenesis_of_disease_involves_gene
- BIRC3/MALT1 Fusion Gene [NCIt concept]
- MALT1 Gene [NCIt concept]
- MALT1 wt Allele [NCIt concept]

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