HRAS wt Allele

Preferred Label : HRAS wt Allele;

NCIt synonyms : HRAS1; C-HA-RAS1; RAS Gene; RASH1; H-ras; H-RASIDX; C-BAS/HAS; CTLO; Ha-ras; C-H-RAS; HRas Proto-Oncogene, GTPase wt Allele; v-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog Gene; Harvey Rat Sarcoma Viral Oncogene Homolog Gene; p21ras; HAMSV;

NCIt definition : Human HRAS wild-type allele is located in the vicinity of 11p15.5 and is approximately 3 kb in length. This allele, which encodes GTPase HRas protein, is involved in cellular mitogenesis. Mutations of HRAS are implicated in Costello syndrome, bladder cancer and oral squamous cell carcinoma.;

GenBank Accession Number : NM_005343;

Details

Origin ID

C52545;

UMLS CUI

C1705572;

Currated CISMeF NLP mapping
- genes, ras [MeSH Descriptor]
- genes, ras [MeSH concept]
OMIM relation
- Hras protooncogene, gtpase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Oral Cavity Squamous Cell Carcinoma [NCIt concept]
- Thyroid Gland Follicular Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- HRAS Gene Amplification [NCIt concept]
gene_has_physical_location
- 11: 525550-522242 [NCIt concept]
gene_in_chromosomal_location
- 11p15.5 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Costello Syndrome [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Angiogenesis Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Aspirin Inhibition of Platelet Activation Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- CCR3 Signaling Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- CXCR4 Signaling Pathway [NCIt concept]
- Cadmium Induction Pathway [NCIt concept]
- Calpain-2 Cell Motility Pathway [NCIt concept]
- Cardiac Hypertrophy Pathway [NCIt concept]
- Cell Cycle Progression Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- EPO Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- HBx Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- IGF-1 Signaling Pathway [NCIt concept]
- IGF1R Antiapoptosis Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL3 Signaling Pathway [NCIt concept]
- IL6 Signaling Pathway [NCIt concept]
- Inhibition of Cellular Proliferation by Gleevec Pathway [NCIt concept]
- Inhibition of Matrix Metalloproteinases Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Longevity Pathway [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Macrophage Differentiation Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Mucosal Healing Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Nerve Growth Factor Pathway [NCIt concept]
- Neuronal Survival Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Oocyte Maturation Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Ras Signaling Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- SRF Activation Pathway [NCIt concept]
- Splicing Regulation Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
- Trka Receptor Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_plays_role_in_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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