NCIt definition : Human KRIT1 wild-type allele is located within 7q21-q22 and is approximately 102 kb
in length. This allele, which encodes Krev interaction trapped protein 1, may play
a role in integrin signaling modulation. Mutations in the gene, which encode for products
that terminate prematurely, are a factor in familial cerebral cavernous malformations.;