AFF4 wt Allele

Preferred Label : AFF4 wt Allele;

NCIt synonyms : AF5Q31; ALL1 Fused Gene From 5q31 Gene; AF4/FMR2 Family Member 4 wt Allele; AF5Q31 Gene; AF5Q31 wt Allele; MCEF; CHOPS; AF4/FMR2 Family, Member 4 Gene; HSPC092;

NCIt definition : Human AFF4 wild-type allele is located in the vicinity of 5q31 and is approximately 88 kb in length. This allele, which encodes AF4/FMR2 family member 4 protein, is involved in transcriptional regulation. A chromosomal aberration involving this gene and the MLL gene, insertion ins(5;11)(q31;q13q23), is associated with acute lymphoblastic leukemia.;

GenBank Accession Number : AF197927;

Details

Origin ID

C52504;

UMLS CUI

C1704937;

OMIM relation
- Alf transcription elongation factor 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Acute Lymphoblastic Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 132327181-132244244 [NCIt concept]
gene_in_chromosomal_location
- 5q31 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients