BCL9 wt Allele

Preferred Label : BCL9 wt Allele;

NCIt synonyms : BCL9, Transcription Coactivator Gene; LGS; Legless, Drosophila, Homolog of Gene; BCL9 Transcription Coactivator wt Allele; B-Cell CLL/Lymphoma 9 Gene;

NCIt definition : Human BCL9 wild-type allele is located in the vicinity of 1q21 and is approximately 85 kb in length. This allele, which encodes B-cell lymphoma 9 protein, may be involved in the regulation of Wnt protein mediated signaling. Altered expression of this gene, which is the result of a translocation t(1;14)(q21;q32), is associated with acute lymphoblastic leukemia.;

GenBank Accession Number : NM_004326;

Details

Origin ID

C52490;

UMLS CUI

C1706883;

False automatic mappings
- Trichorhinophalangeal syndrome, type II [OMIM Phenotype]
OMIM relation
- B-cell cll/lymphoma 9 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- B Acute Lymphoblastic Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 144237996-144322828 [NCIt concept]
gene_in_chromosomal_location
- 1q21 [NCIt concept]
gene_plays_role_in_process
- Developmental Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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