GRB2 wt Allele

Preferred Label : GRB2 wt Allele;

NCIt synonyms : ASH; Grb3-3; EGFRBP-GRB2; Growth Factor Receptor-Bound Protein 2 Gene; NCKAP2; MST084; Growth Factor Receptor Bound Protein 2 wt Allele; MSTP084; Growth Factor Receptor-Bound Protein 3 Gene; Abundant SRC Homology Gene; Epidermal Growth Factor Receptor-Binding Protein GRB2 Gene;

NCIt definition : Human GRB2 wild-type allele is located within 17q24-q25 and is approximately 88 kb in length. This allele, which encodes growth factor receptor-bound protein 2, plays a role in epidermal growth factor-mediated signal progression.;

GenBank Accession Number : NM_002086;

Details

Origin ID

C52395;

UMLS CUI

C1708154;

Automatic exact mappings (from CISMeF team)
- Ash [DeCS]
- Ash (organism) [SNOMED CT concept]
- Cardiomyopathy, familial hypertrophic, 1 [OMIM Phenotype]
- grb2 adaptor protein [MeSH Descriptor]
OMIM relation
- Growth factor receptor-bound protein 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 17: 70913384-70825753 [NCIt concept]
gene_in_chromosomal_location
- 17q24-q25 [NCIt concept]
gene_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Dorso-Ventral Axis Formation Pathway [NCIt concept]
- EGF Receptor Downregulation by CBL Pathway [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- EPO Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- HBx Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- IGF-1 Signaling Pathway [NCIt concept]
- IGF1R Antiapoptosis Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL3 Signaling Pathway [NCIt concept]
- IL4 Signaling Pathway [NCIt concept]
- IL6 Signaling Pathway [NCIt concept]
- Inhibition of Cellular Proliferation by Gleevec Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Mucosal Healing Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Nerve Growth Factor Pathway [NCIt concept]
- Neuronal Survival Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- PTEN-Dependent Cell Cycle Arrest and Apoptosis Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- SRC Tyrosine Kinase Activation Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
- Trka Receptor Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_plays_role_in_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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